HYBRID EVENT: You can participate in person at Madrid, Spain or Virtually from your home or work.

5th Edition of Global Conference on Surgery and Anaesthesia

September 05-07, 2024 | Hybrid Event

September 05 -07, 2024 | Madrid, Spain
GCSA 2022

Avishek Samaddar

Avishek Samaddar, Speaker at Surgery Conference 2022
University Hospitals of North Midlands, United Kingdom
Title : Effects of Cardiopulmonary Bypass Temperature in Adult Cardiac surgery: A Single-Centre Parallel-group Open Randomised Controlled Trial


Background and Aim:
Cardiopulmonary bypass is an integral and essential part of cardiac surgery. Over the years, there has been an increasing debate over the cardiopulmonary temperatures and its effects on post-operative patient outcome. While some studies have shown beneficial effects of hypothermic cardiopulmonary bypass while others have shown that normothermia is the way to go. Hence further studies are necessary to assess the effects of cardiopulmonary bypass temperatures on patient outcomes. The aim of our study was to assess the merits and demerits in terms of patient outcomes of normothermic CPB over hypothermic CPB during open heart surgeries in adult patients.
A total of 100 adult patients undergoing Coronary artery bypass grafting or other forms of open heart surgery at Post Graduate Institute of Medical Education and Research, Chandigarh, India between January 2016 and April 2017 were randomised into 2 groups of 50 each. While one arm was operated using normothermic CPB, the other was operated on hypothermic CPB. Post –operative outcomes were compared between the two groups. Statistical analysis was done using SPSS software. The co-primary end points were inotropic and ventilatory requirements along with post-operative hospital stay. Several secondary including transfusion requirements, cardiac arrhythmias, post-operative bleeding and ventricular function were also assessed.
Normothermic CPB resulted in reduced post-operative ICU and hospital stay, less requirements of post-operative mechanical ventilation, fewer derangements in coagulation profile and post-operative drain output, less transfusion requirements in comparison to the patients who were operated using hypothermic CPB. However there was no significant difference in renal function, mean blood sugar levels, postoperative fever, wound infection, arrhythmia and need for re-exploration among the two groups.
From the results of our study, we recommend that normothermic cardiopulmonary bypass is associated with better post-operative outcomes although adequate myocardial protection is always necessary.


Avishek Samaddar did his basic medical degree from R.G. Kar Medical College, Kolkata. Subsequently he did his Masters in General Surgery followed by Mch Cardiovascular and Thoracic Surgery from the Post Graduate Institute of Medical Education and Research, Chandigarh, one of the premier institutes of India. Subsequently he worked as a consultant in NH Rabindranath Tagore International Institute of Cardiac Sciences, Kolkata from 2018 to 2021 before moving to the United Kingdom to work at Alder Hey Children’s Hospital, Liverpool. He is presently associated with the University Hospitals of North Midlands, Stoke-on Trent and has published multiple articles and is also an active reviewer of multiple journals.