Background: Early detection of polyposis syndrome based on clinical features and radiological investigations is important to rule out early malignancy risk. Here we discuss four (4) polyposis cases and their varied presentation and management as follows.
Case 1 was a 10year old male presenting with double intussusception secondary to polyps suggestive of peutzjeghers polyposis on histology by the presence of a smooth muscle arborization within the lamina propria.
Case 2 was a 28 years old male who was admitted for blood in stools which on endoscopic examination had multiple hamartomatous intestinal polyps had alopecia and nail changes pointing towards Cronkhite Canada syndrome.
Case 3 was a 19 years old male with a history of mass per rectum and PR bleed was diagnosed to have extensive multiple polyps extending from caecum to rectum suggestive of juvenile rectal polyposis
Case 4 was a 45years old male with a history of loss of appetite, generalized weakness, and intermittent abdominal pain which on contrast-enhanced computed tomography and endoscopic evaluation was suggestive of dual malignancy of stomach and colon.