Title : Efficacy and safety of kahook dual blade goniotomy and trabecular micro-bypass stent (Istent inject) In combination with cataract extraction: A retrospective study
Abstract:
Purpose: To compare the efficacy and safety of Kahook Blade Dual (KDB) goniotomy and trabecular micro-bypass stent (iStent inject) for microinvasive glaucoma surgery (MIGS) with cataract extraction.
Methods: Our study included all participants who underwent either MIGS procedure combined with cataract extraction. Data collected included pre-op and post-op IOP, IOP-lowering medications, BCVA, adverse events, and need for IOP-lowering surgery. The primary outcome was the proportion of patients in each group achieving a 20% reduction in IOP.
Results: A total of 66 eyes were included in the iStent inject group and 25 eyes in the KDB group. Mean follow-ups were 12 months for both groups. Both the iStent inject and KDB had similar success rates in achieving a 20% reduction in IOP (67% and 60% respectively) with no significant statistical difference (p=0.55). No major complications occurred. Changes in IOP and medications were not significantly different between groups.
Conclusions: Both KDB and iStent Inject are safe and effective options for MIGS with cataract extraction. However, larger patient populations are needed to compare these procedures head-to-head.
Précise: The study compared the effectiveness and safety of KDB and iStent inject for microinvasive glaucoma surgery (MIGS) with cataract extraction. Data collected included IOP, medications, BCVA, adverse events, and need for IOP-lowering surgery. 66 patients (91 eyes) participated, with both groups having similar success rates in achieving a 20% reduction in IOP. KDB and iStent inject were found to have equivalent IOP-lowering effects, with no significant difference in complications.
Backgroud statement: North America's first study comparing KDB and iStent inject procedures, with a large sample size. A single surgeon performed surgeries using a standardized protocol, treating a broad range of glaucoma severity, generating comprehensive data.
Audience Takeway Notes:
- Gain insights into the efficacy and safety comparison between KDB goniotomy and iStent inject for MIGS with cataract extraction.
- Apply the study's findings to clinical practice to enhance patient care in glaucoma treatment.
- Understand the statistical significance and success rates of the procedures, which may guide surgical decisions.
